Sharon Mates,Robert Davis,Lawrence P. Wennogle,Peng Li,John Charles Tomesch,Qiang Zhang
申请号:
US13642652
公开号:
US08993572B2
申请日:
2011.04.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The invention relates to particular substituted heterocycle fused gamma-carbolines of formula I:as described herein, their prodrugs, in free, solid, pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use in the treatment of diseases involving 5-HT2A receptor, serotonin transporter (SERT) and/or pathways involving dopamine D2 receptor signaling systems.