Mesoporous silica compositions for modulating immune responses

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专利权人:

PRESIDENT AND FELLOWS OF HARVARD COLLEGE

发明人:

KIM, Jaeyun,LI, Weiwei Aileen,MOONEY, David J.

申请号：

AU2018202973

公开号：

AU2018202973A1

申请日:

2018.04.30

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

#$%^&*AU2018202973A120180517.pdf#####ABSTRACT A composition comprising mesoporous silica rods comprising an immune cell recruitment compound and an immune cell activation compound, and optionally 5 comprising an antigen such as a tumor lysate. The composition is used to elicit an immune response to a vaccine antigen.1/28 20 gm* EHT =10.75 kV Signal A =SE1 Sample ID Peltier Temp 20.0 C Mag = 1.04 KX WD 19.0 mm Chamber 1.33e-003 Pa Humidity 0.0% FIG. 1 90%- E MHCll+ o 80%- 0 CD86+ u 70%x60%'50%40%E 30%20%10%0%- - -r " Control 2 pm 30 pm 100 pm CpG FIG. 2

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