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METHOD OF PRODUCING IN VITRO TESTICULAR CONSTRUCTS AND USES THEREOF
专利权人:
发明人:
Samuel Pendergraft,Hooman Sadri-Ardekani,Anthony Atala,Colin Bishop
申请号:
US15294154
公开号:
US20170107483A1
申请日:
2016.10.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A cell composition composed of spermatogonial stem cells, Sertoli cells, Leydig cells and optionally peritubular cells, is provided, as is a culture composition, artificial testicular construct, hydrogel composition, and device containing the same. A method for using the device as a physiologically relevant in vitro model of human testicular function to screen compounds for pharmacological or toxicological activity is also provided.
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