Jacques F. Banchereau;Anne-Laure Flamar;Gerard Zurawski
发明人:
Gerard Zurawski,Jacques F. Banchereau,Anne-Laure Flamar
申请号:
US13208993
公开号:
US20120039916A1
申请日:
2011.08.12
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compositions and methods for enhancing an immune response with an adjuvant composition comprising: an anti-dendritic cell (DC)-specific antibody or fragment thereof conjugated to at least a portion of a TLR agonist; and a pharmaceutically acceptable carrier are disclosed herein. The conjugate and agonist are each comprised in an amount such that, in combination with the other, are effective to produce the immune response in a human or animal subject in need of immunostimulation.