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Rapidly dispersible, fine-particle film-coating composition which is in powder form, is not prone to segregation and is based on polyvinyl alcohol-polyether graft copolymers characterized by particular physical stability and low asperity
专利权人:
Karl Kolter
发明人:
Karl Kolter,Maximilian Angel,Andreas Habich
申请号:
US11631368
公开号:
US09763888B2
申请日:
2005.06.22
申请国别(地区):
US
年份:
2017
代理人:
摘要:
A rapidly dispersible, fine-particle film-coating composition which is in powder form and is not prone to segregation for coating pharmaceutical dosage forms, consisting ofa) 40-90% by weight of a polyvinyl alcohol-polyether graft copolymer (component A),b) 1-20% by weight of a polyvinylpyrrolidone or of a vinylpyrrolidone-vinyl acetate-copolymer with a K value of from 10 to 100 (component B)c) 10-60% by weight of organic or inorganic pigments having an average particle size of less than 8 μm (component C)d) 0.5-15% by weight of a surfactant having an HLB of greater than 10 (component D) ande) 0-30% by weight of further customary coating ingredients (components E),in which the particles of component C are embedded in a coherent polymer matrix,where the total amount of components A to E is 100% by weight.
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