The invention provides for the human antibodies that bind to human platelet-derived growth factor receptor alpha (PDGFR alpha), preferably olaratumab, for the treatment of gastrointestinal stromal tumors with PDGFR alpha mutations including D842V.本發明提供結合至人類血小板來源生長因子受體α(PDGFRα)之人類抗體,較佳奧拉木單抗(olaratumab),其用於治療具有PDGFRα突變(包括D842V)之胃腸道基質瘤。
