Wilson, Nicholas S.,Waight, Jeremy D.,Breous-Nystrom, Ekaterina V.,Seibert, Volker,Ritter, Gerd,Schaer, David,Hirschhorn-Cymerman, Daniel,Merghoub, Taha,Van Dijk, Marc
申请号：
AU2016364891
公开号：
AU2016364891A1
申请日:
2016.12.02
申请国别(地区):
AU
年份:
2018
代理人:
摘要：
The present disclosure provides antibodies that specifically bind to human OX40 receptor (OX40) and compositions comprising such antibodies. In a specific aspect, the antibodies specifically bind to human OX40 and modulate OX40 activity, e.g., enhance, activate, or induce OX40 activity, or diminish, deactivate, or suppress OX40 activity. The present disclosure also provides methods for treating disorders, such as cancer, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., enhances, activates, or induces OX40 activity. Also provided are methods for treating autoimmune or inflammatory diseases or disorders, by administering an antibody that specifically binds to human OX40 and modulates OX40 activity, e.g., diminishes, deactivates, or suppresses OX40 activity.
