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Heterocyclic compound and use thereof
专利权人:
Masanori Okaniwa
发明人:
Masanori Okaniwa
申请号:
US13132253
公开号:
US08697874B2
申请日:
2009.11.30
申请国别(地区):
US
年份:
2014
代理人:
摘要:
A compound represented by formula (I) or a salt thereof, which has a potent Raf inhibitory activity.In formula (I), R1 represents an optionally substituted C1-6 alkyl, etc. X represents —O— or —NR2— (wherein R2 represents a hydrogen atom or a C1-6 alkyl) Y represents a group represented by formula 2 (2i or 2ii)(wherein ring A represents an optionally substituted benzene ring Z represents a group represented by (1) —NR3CO—W1—, (2) —NR3CO—W1—O—, (3) —NR3CO—W1—O—W2—, (4) —NR3CO—W1—S—, (5) —NR3CO—W1—NR4—, (6) —NR3COO—, (7) —NR3COO—W1—, (8) —NR3CO—CO—, or (9) —NR3CONR4— (wherein R3 and R4 each represents a hydrogen atom, etc., and W1 and W2 each represents an optionally substituted C1-6 alkylene, etc.) and R5 represents an optionally substituted five- or six-membered ring group.
来源网站:
中国工程科技知识中心
来源网址:
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