Robert Kiss;Philippe Neven;Didier Serteyn;Didier Cataldo;Natacha Rocks;Veronique Mathieu;Eva Scheer
发明人:
Philippe Neven,Didier Serteyn,Jacques Delarge,Robert Kiss,Veronique Mathieu,Didier Cataldo,Natacha Rocks
申请号：
US12995126
公开号：
US08772265B2
申请日:
2009.05.26
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to the medical field. In a first aspect the present invention relates to novel water soluble cyclodextrin-curcumin complexes having a pharmacological activity, in particular an anti-tumor and/or anti-inflammatory activity, and improved physico-chemical properties. In a second aspect, the present invention relates to a method for preparation of said water soluble curcumin derivatives. The invention further relates in a third aspect to a pharmaceutical composition comprising an effective amount of said water soluble curcumin derivatives. In a fourth aspect, the present invention concerns the use of said water soluble cucumin derivatives as a medicament and the use of said water soluble curcumin derivatives for the preparation of a medicament for the treatment of cancer and inflammatory diseases. In a fifth aspect, the present invention relates to the use of a pharmaceutical composition comprising said water soluble curcumin derivatives in the treatment of cancer and inflammatory diseases and to a new pharmaceutical composition comprising said water soluble curcumin derivatives.
