A safety sleeve system for syringes and other needle-based devices prevents accidental needle sticks after use of the syringe. The safety sleeve system allows an easy mechanical cover that, once actuated, locks over the exposed needle for safe coverage and disposal, or, in a sterile situation, allows for exposure of a clean needle. The safety sleeve system minimally alters an existing syringe and allows for identical use and function, with only an outer sleeve cover that follows tracks embossed on the exterior of the existing syringe. This sleeve cover can be twisted and locked in an operation position, where the needle extends from the sleeve cover, or in a safety position, where the needle is encased by the sleeve cover.
