MA, DANGSHE,OLSON, WILLIAM C.,MORRIS, STEPHEN,ISRAEL, ROBERT
申请号：
PL09789284
公开号：
PL2326350T3
申请日:
2009.09.08
申请国别(地区):
PL
年份:
2014
代理人:
摘要：
Methods of killing prostate-specific membrane antigen (PSMA)-expressing, taxane-resistant cancer cells are provided. In particular, PSMA-expressing, taxane-resistant cancer cells are contacted with an antibody-drug conjugate (ADC) that comprises an antibody or antigen-binding fragment thereof that specifically binds to PSMA conjugated to monomethylauristatin norephedrine or monomethylauristatin phenylalanine.
