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DENDRITIC-CELL-TARGETED PEPTIDE, FUSION PEPTIDE UTILIZING SAID PEPTIDE, AND VACCINE UTILIZING SAID FUSION PEPTIDE
专利权人:
The Research Foundation for Microbial Diseases of Osaka University
发明人:
Yasuo Yoshioka
申请号:
US16335625
公开号:
US20190300585A1
申请日:
2017.09.21
申请国别(地区):
US
年份:
2019
代理人:
摘要:
The purpose of the present invention is to provide a peptide that is capable of efficiently delivering an antigen to dendritic cells and improving the vaccine effects of the antigen. A peptide that has at least one motif sequence comprising the amino acid sequence of sequence listing 1, or an amino acid sequence comprising the aforementioned amino acid sequence, but in which a mutation has been induced in the amino acid residue at the first and/or second position of the amino acid sequence, is bound to an antigen protein or an antigen peptide to efficiently deliver the antigen protein or antigen peptide to dendritic cells, allowing for significantly superior vaccine effects to be exhibited.
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