Samuel S. Murray;Keyvan Behnam;Elsa J. Brochmann-Murray
发明人:
Samuel S. Murray,Keyvan Behnam,Elsa J. Brochmann-Murray
申请号:
US10587313
公开号:
US08188219B2
申请日:
2005.01.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A cyclized peptide designated BMP Binding Peptide (BBP) is a synthetic peptide that avidly binds rhBMP-2. BBP increases the over-all osteogenic activity of rgBMP-2, increases the rate at which rhBMP-2 induces bone formation, and BBP induces calcification alone. Compositions and substrates including BBP, and methods of using BBP are useful in therapeutic, diagnostic and clinical applications requiring calcification and osteogenesis.