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T-cell modulatory multimeric polypeptides and methods of use thereof
专利权人:
Cue Biopharma; Inc.
发明人:
Seidel III, Ronald D.,Chaparro, Rodolfo
申请号:
AU2017268348
公开号:
AU2017268348A1
申请日:
2017.05.17
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present disclosure provides T-cell modulatory multimeric polypeptides comprising two different immunomodulatory polypeptides, at least one of which is a variant immunomodulatory polypeptide. The present disclosure provides nucleic acids comprising nucleotide sequences encoding the T-cell modulatory multimeric polypeptides, and host cells comprising the nucleic acids. The present disclosure provides methods of modulating the activity of a T cell the methods comprise contacting the T cell with a T-cell modulatory multimeric polypeptide of the present disclosure.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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