POLYTHERAPIES FAISANT APPEL A DES MODULATEURS DU RECEPTEUR DE FARNESOIDE X (FXR)

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专利权人:

LTD.;AKARNA THERAPEUTICS

发明人:

PRATT, BENJAMIN ANTHONY,MOHAN, RAJU

申请号：

CA3025007

公开号：

CA3025007A1

申请日:

2017.05.25

申请国别(地区):

CA

年份:

2017

代理人:

摘要：

Described herein are methods of treating a metabolic disorder in an individual in need thereof, comprising co-administering to the individual a therapeutically effective amount of an FXR modulator, and at least one second agent that is an CCR2/CCR5 antagonist, ASKl inhibitor, DPP-IV inhibitor, caspase protease inhibitor, SGLT2 inhibitor, acetyl-CoA carboxylase (ACC) inhibitor, diacyl glycerol acyltransferase-1 inhibitor, sodium -bile acid cotransporter-inhibitor, TLR-4 antagonist, PPAR alpha/delta agonist, or GLP-1 agonist, or a combination thereof.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/