ALESSANDRO BOEZIO,ANGEL GUZMAN-PEREZ,BENJAMIN C. MILGRAM,ISAAC E. MARX,JOHN STELLWAGEN,MATTHEW WEISS,THOMAS DINEEN
申请号:
BR112017018755
公开号:
BR112017018755A2
申请日:
2016.03.02
申请国别(地区):
BR
年份:
2018
代理人:
摘要:
as defined in the specification, an enantiomer, diastereomer, atropisomer thereof, or a mixture thereof, or pharmaceutically acceptable salts thereof, that are inhibitors of voltage-gated sodium channels, in particular Nav 1.7. The compounds are useful for the treatment of diseases treatable by inhibition of sodium channels such as pain disorders, cough, or itch. Also provided are pharmaceutical compositions containing compounds of the present invention.