An animal enclosure with a wall assembly and a panel that is configured to couple to the wall assembly. The wall assembly includes a plurality of walls that are coupled together to define an interior space. The walls define an opening configured for fluid connection to a ventilation system. When the panel is coupled to the wall assembly, the panel divides the interior space into a vent space, which is in fluid communication with the opening, and a living space. A vent opening formed in the panel is configured to place the living space in fluid communication with the vent space. The panel may be removably coupled to the wall assembly. The panel may include a damper system for selectively opening and closing the vent opening.
