Fraser, Christopher,Kishimoto, Takashi Kei,Maldonado, Roberto A.
申请号:
AU2019232935
公开号:
AU2019232935A1
申请日:
2019.09.20
申请国别(地区):
AU
年份:
2019
代理人:
摘要:
#$%^&*AU2019232935A120191017.pdf#####ABSTRACT Disclosed are synthetic nanocarrier compositions, and related methods, comprising MHC Class I-restricted and/or MHC Class II-restricted epitopes associated with undesired CD8+ T cell responses and immunosuppressants that provide tolerogenic immune responses against antigens that comprise the epitopes. See Fig. 5.WO 2012/149265 PCT/US2012/035378 3/3 100Ln 80S6020 N/A 0 Ln z z DNo imm OVA±CpG sc Fig. 4 1.5Q u0.50 0.0-r in 0>; z Fig. 5 CI T 7 T TI'nT T T CI T TTV'U''U /T, T Tl T'