Christian Klein;Christian Gerdes;Valeria G. Nicolini;Pablo Umana;Ekkehard Moessner
发明人:
Christian Gerdes,Christian Klein,Ekkehard Moessner,Valeria G. Nicolini,Pablo Umana
申请号:
US13367881
公开号:
US20120258073A1
申请日:
2012.02.07
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention provides combinations of (a) an immunoconjugate comprising at least one antigen-binding moiety and an effector moiety, and (b) an antibody engineered to have increased effector function, for use in treating a disease in an individual in need thereof. Further provided are pharmaceutical compositions comprising the combinations, and methods of using them.