Kohane, Daniel,Yeo, Yoon,Given, Peter,Langer, Robert
申请号：
ES12000252
公开号：
ES2654616T3
申请日:
2008.08.12
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
A complex coacervate delivery system comprising an aqueous dispersion of complex coacervates； in which the complex coacervates are not agglomerated but comprise a single crust encapsulating a single core, a single core comprising at least one cationic food grade polymer and at least one food grade anionic polymer； wherein the single core comprises at least one lipophilic nutrient； in which the complex coacervates in the complex coacervate delivery system release the lipophilic nutrient in a manner controlled by the pH in the part of the gastrointestinal tract below the stomach, where the pH is neutral or alkaline, in which at least a majority of The complex coacervates have a particle size in the range of 0.1 μm to 5.0 μm, in which the cationic polymer comprises at least one of dairy products proteins, whey proteins, caseins and fractions thereof, gelatin, corn zein protein, bovine serum albumin, ovalbumin, cereal protein extracts, vegetable proteins, microbial proteins, legume proteins, nut proteins, peanut proteins, chitosan, Eudragit E, Eudragit E 100 and Eudragit E PO, or wherein the anionic polymer comprises at least one of pectin, carrageenan, alginate, xanthan gum, modified celluloses, carboxymethyl cellulose, gum arabic, gh gum atti, karaya gum, tragacanth gum, garrofín gum, guar gum, zaragatona seed gum, quince seed gum, laryx gum, stractan gum, agar, furcelarana, modified starches, gellan gum and fucoidan, in which the ratio of Weight to weight of cationic polymer to anionic polymer is 10: 1 to 1:10.Un sistema de suministro de coacervados complejos que comprende una dispersión acuosa de coacervados complejos； en que los coacervados complejos son no aglomerados sino que comprenden una corteza única que encapsula un núcleo único, núcleo único que comprende al menos un polímero catiónico de calidad alimenticia y al menos un polímero aniónico de calidad alimenticia； en que el núcleo único comprende al menos un nutriente lipófilo； en que los coacervados complej
