ACIDES NUCLEIQUES SUPPRESSEURS DE L'EXPRESSION D'APCS

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专利权人:

KYOWA KIRIN CO.; LTD.

发明人:

ARIYAMA, HIROYUKI,MURAKAMI, TAKUYA,IMAEDA, TAKASHI,MIYAZAWA, TATSUYA

申请号：

CA3065149

公开号：

CA3065149A1

申请日:

2018.05.31

申请国别(地区):

CA

年份:

2018

代理人:

摘要：

The present invention provides a double-strandednucleic acid consisting of a sense-strand nucleic acidand an antisense-strand nucleic acid and comprising adouble-strand region having at least 11 base pairs, forsuppressing expression of APCS gene, in which anoligonucleotide chain having a chain length of at least17 nucleotides and at most 30 nucleotides in theantisense-strand nucleic acid is complementary to atarget APCS mRNA sequence comprising a base sequence setforth in any one of SEQ ID NOS: 1288 to 1930.

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