FORMES SOLIDES DE (1R,4R)-6'-FLUORO-(N,N-DIMÉTHYL)-4-PHÉNYL-4',9'- DIHYDRO-3'H-SPIRO[CYCLOHEXANE-1,1'-PYRANO[3,4-B]INDOL]-4-AMINE ET D'ACIDE SULFURIQUE
The invention relates to solid forms of (1r,4r)-6'-fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro- 3'H-spiro[cyclohexane-1,1'-pyrano[3,4b]indol]-4-amine and sulfuric acid such as (1r,4r)-6'- fluoro-N,N-dimethyl-4-phenyl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano[3,4b]indol]-4- amine sulfate or hemi-sulfate, in particular crystalline forms and/or amorphous forms thereof, pharmaceutical compositions and medicaments comprising these solid forms, the use of these solid forms as well as to a process for obtaining them.Cette invention concerne des formes solides de (1R,4R)-6'-fluoro- N,N-diméthyl-4-phényl-4',9'-dihydro-3'H-spiro[cyclohexane-1,1'-pyrano- [3,4-b]indol]-4-amine et d'acide sulfurique telles que le sulfate ou l'hémi-sulfate de (1R,4R)-6'-fluoro-N-N-diméthyl-4-phényl-4',9'- dihydro-3'H-spiro[cyclohexane-1,1'-pyrano-[3,4-b]indol]-4-amine, en particulier leurs formes cristallines et/ou amorphes ； des compositions pharmaceutiques et des médicaments contenant ces formes solides ； l'utilisation de ces formes solides ainsi qu'un procédé pour les obtenir.
