MUI CHEUNG,HILARY SCHENECK EIDAM,MICHAEL P. DEMARTINO,ZHEN GONG,AMY HUIPING GUAN,KAUSHIK RAHA,CHENGDE WU,HAIYING YANG,HAIYU YU,ZHILIU ZHANG
申请号：
DO2015000244
公开号：
DOP2015000244A
申请日:
2015.09.15
申请国别(地区):
DO
年份:
2015
代理人:
摘要：
The invention refers to a new compound of pentachlorobenzene inhibitor which is reconstituted in the process of blood transfusion,Pharmaceutical ingredients containing these substances, their preparation procedures, and procedures used alone or in combination for treatment, normalization of gastrointestinal sensitivity, motility and / or secretion and / or abdominal disorders or diseases, and / or production of therapeutic related practical drugs Diseases related to ret dysfunction or diseases in which the modularization of RET activity can bring therapeutic benefits, including but not limited to all categories of irritant bowel, including major diarrhea, major constipation or the spread of alternate excreta,Functional abdominal injury functional constipation functional diarrhea functional intestinal disorder functional abdominal pain syndrome functional abdominal spasm functional inflammation functional esophageal disorder functional gastrointestinal disorder functional spasm functional anorexic gastritis intestinal inflammation Diffuse diseases, such as: cell-free cancer, liver cancer, rectal cancer, spinal cord thyroid cancer, folk thyroid cancer, anaerobic thyroid cancer, mumps thyroid cancer, mumps thyroid cancer, brain tumor, peritoneal cavity cancer, skin cancer, other lung cancer,(head and neck, blood cells, neurocytoma, von Hippel Lindau thrombus and RI tumor, breast cancer, fallopian tube cancer, ovarian cancer, thrombus cancer, transitional red cell cancer, uterine cancer, body and stomach cancer, gallbladder cancer, adenoma and any malignant tumor) Quintasa RET activity increasedESTA INVENCIÓN SE REFIERE A NUEVOS COMPUESTOS QUE SON INHIBIDORES DE LA QUINASA REORGANIZADA DURANTE LA TRANSFECCIÓN (RET), A COMPOSICIONES FARMACÉUTICAS QUE LOS CONTIENEN, A LOS PROCEDIMIENTOS PARA SU PREPARACIÓN, Y A SU USO EN TERAPIA, SOLOS O COMBINADOS, PARA LA NORMALIZACIÓN DE LA SENSIBILIDAD, LA MOTILIDAD Y/O LA SECRECIÓN GASTROINTESTINAL Y/O TRASTORNOS O ENFERMEDADES ABD
