MROCZKIEWICZ, MICHAL,STYPIK, BARTOSZ,BUJAK, ANNA,SZYMCZAK, KRZYSZTOF,GUNERKA, PAWEL,DUBIEL, KRZYSZTOF,WIECZOREK, MACIEJ,PIECZYKOLAN, JERZY
申请号：
CA3059829
公开号：
CA3059829A1
申请日:
2018.05.10
申请国别(地区):
CA
年份:
2018
代理人:
摘要：
A compound or its acid addition salt of the general formula (I), wherein R1 represents phenyl substituted with one or two substituents selected from the group consisting of halogen and C1-C3 alkoxyl, or 6-membered heteroaryl with 1 or 2 nitrogen atoms, which is unsubstituted or substituted with a substituent selected from the group consisting of -NH2, halogen, alkyl C1-C4, alkoxyl C1-C3, and 6-membered heterocyclyl comprising 1 or 2 heteroatoms selected from the group consisting of N and O. The compound has the activity of kinase JAK1/JAK3 inhibitor and can find use in the treatment of chronic inflammatory and autoimmunological diseases.
