Matthias Engel,Wolfgang Fröhner,Adriane Stroba,Ricardo M. Biondi
申请号:
US13124773
公开号:
US08912186B2
申请日:
2009.10.16
申请国别(地区):
US
年份:
2014
代理人:
摘要:
The invention provides specific small molecule compounds that allosterically regulate the activity or modulate protein-protein interactions of AGC protein kinases and the Aurora family of protein kinases, methods for their production, pharmaceutical compositions comprising same, and their use for preparing medicaments for the treatment and prevention of diseases related to abnormal activities of AGC protein kinases or of protein kinases of the Aurora family.