#$%^&*AU2011200507B220120906.pdf#####C NRPorbl CC TXS3454189_ DOC-7/02/201I PIPERIDINYL PROSTAGLANDIN E ANALOGS Abstract 5 The present invention provides a method of treating ocular hypertension or glaucoma which comprises administering to an animal having ocular hypertension or glaucoma therapeutically effective amount of a compound represented by the general formula (I)； wherein X, Y, Z, D and R3 are as defined in the specification. Also disclosed are compounds comprising formula (II) or a pharmaceutically acceptable salt or a prodrug 10 thereof； wherein A, X, J, and R3 are as defined in the specification. Also disclosed are compounds having an a and an to chain comprising formula (III) or formula (IV) or derivatives thereof, as defined in the specification or pharmaceutically acceptable salts or prodrugs thereof.
