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Stable micelles formed with diblock copolymers of critical micelle concentration copolymer and temperature-sensitive copolymer
专利权人:
Ging-Ho Hsiue
发明人:
Ging-Ho Hsiue,Chun-Liang Lo,Sheng-Jie Lin,Hsieh-Chih Tsai
申请号:
US12411267
公开号:
US08299178B2
申请日:
2009.03.25
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A novel class of mixed micelles formed with critical micelle concentration (Cmc) characters diblock copolymer, and temperature-sensitive characters diblock copolymer were disclosed. The mixed micelles possess complementary effects in adjusting external temperature shift (storage vs. body temperature) and concentration change (dilution after intravenous injection). The mixed micelles of the present invention can serve as a potential injectable drug delivery system for anticancer drugs, such as doxorubicin and many others.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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