PREPARAT PRZECIWCIAŁA ANTY-ALFA4BETA7

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专利权人:

Inc.;Millennium Pharmaceuticals

发明人:

DILUZIO WILLOW,TRUONG NOBEL T.,VARGA CSANAD M.,PALANIAPPAN VAITHIANATHAN,BROWN JASON,FOX IRVING H.,SCHOLZ CATHERINE,SC

申请号：

PL12721093

公开号：

PL2704798T3

申请日:

2012.05.02

申请国别(地区):

PL

年份:

2017

代理人:

摘要：

Antibody formulations are described comprising a mixture of a non-reducing sugar, an anti-±4²7 antibody and at least one amino acid. The disclosed formulations have improved stability, reduced aggregate formation, and may retard degradation of the anti-±4²7 antibody therein or exhibit any combinations thereof. The present invention further provides a safe dosing regimen of these antibody formulations that is easy to follow, and which results in a therapeutically effective amount of the anti-±4²7 antibody in vivo.

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