LIU HARLIN,WILLIS CHRIS,BHARDWAJ RENU,COPELAND DIANE, P.,HARIANAWALA, ABIZER,SKELL JEFFREY,MARSHALL JOHN,KOCHLING JIANMEI,PALACE GERARD,PETERSCHMITT JUDITH,SIEGEL CRAIG,CHENG SENG
申请号：
TN2012000237
公开号：
TN2012000237A1
申请日:
2012.05.18
申请国别(地区):
TN
年份:
2013
代理人:
摘要：
The hemitartrate salt of a compound represented by the following structural formula: (Formula I Hemitartrate), which may be used in pharmaceutical applications, are disclosed. Particular single crystalline forms of the Formula (I) Hemitartrate are characterized by a variety of properties and physical measurements. As well, methods of producing crystalline Formula (I) Hemitartrate, and using it to inhibit glucosylceramide synthase or lowering glycosphingolipid concentrations in subjects to treat a number of diseases, are also discussed. Pharmaceutical compositions are also described.
