BURT, JOHN,GODWIN, ANTONY,FRIGERIO, MARK,BADESCU, GEORGE
申请号:
CA2884299
公开号:
CA2884299A1
申请日:
2013.10.11
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
Specific conjugates containing auristatins and a binding protein or peptide, and processes for making them, are described. The conjugates use specific linker technology which gives advantages over known antibody-drug conjugates. Also described are specific conjugates of drugs and a binding protein or peptide in which more than one copy of the drug is present.