Ana Paula Galvao da Silva,Julie DeSander,Jeffrey Behrens,Darius Ghaderi,Mai Zhang,Kristan Meetze
申请号:
US16742434
公开号:
US20200276306A1
申请日:
2020.01.14
申请国别(地区):
US
年份:
2020
代理人:
摘要:
The present invention provides glycan-interacting antibodies and methods for producing glycan-interacting antibodies useful in the treatment and prevention of human disease, including cancer. Such glycan-interacting antibodies include mono clonal antibodies, derivatives, and fragments thereof as well as compositions and kits comprising them. In some embodiments, the present invention provides an antibody having a heavy chain with an amino acid sequence comprising at least 95% sequence identity to SEQ ID NO: 63 and having a light chain with an amino acid sequence comprising at least 95% sequence identity to SEQ ID NO: 64.