The present invention refers to a single piece spacer chamber, a base end and a tip end, the base end having a diameter larger than a diameter of the tip end, single piece chamber is made entirely of a flexible material. A medication container is connected to the tip end. The chamber has a truncated cone shape, a plurality of external zigzag popoid folds circumferentially formed through the external side of the chamber, and a plurality of internal folds circumferentially formed through the internal side of the chamber. The popoid folds have a size that decreases from the base end to the tip end. In a collapsed position each popoid folds against an adjacent popoid and fits entirely inside the adjacent popoid.