MODYFIKOWANE WARIANTY IL-2, KTÓRE SELEKTYWNIE AKTYWUJĄ LIMFOCYTY T REGULATOROWE DO LECZENIA CHORÓB AUTOIMMUNOLOGICZNYCH

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专利权人:

Inc.;Delinia

发明人:

GREVE, JEFFREY

申请号：

PL15831523

公开号：

PL3180020T3

申请日:

2015.08.10

申请国别(地区):

PL

年份:

2019

代理人:

摘要：

The invention described herein is a novel IL-2 protein with selective agonist activity for Regulatory T cells and with an additional amino acid substitution that enable chemical conjugation with Polyethyene Glycol (PEG) that increase circulating half- life compared to the IL-2 selective agonist alone. A preferred IL-2 selective agonist variant is IL2/N88R/C125S/D109C.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/