Curtis J. Henrich,Heidi R. Bokesch,Susan E. Bates,Robert W. Robey,Suneet Shukla,Suresh V. Ambudkar,Michael C. Dean,James B. McMahon
申请号：
US12742039
公开号：
US09114102B2
申请日:
2008.11.05
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Disclosed are methods of enhancing the chemotherapeutic treatment of tumor cells, reducing resistance of a cancer cell to a chemotherapeutic agent, a method of inhibiting ABCG2 or MRP1 in a mammal afflicted with cancer, and a method of increasing the bioavailability of an ABCG2 substrate drug in a mammal. The methods comprise administering peliomycin and other compounds described herein.
