REMOVAL OF RESIDUAL CELL CULTURE IMPURITIES

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专利权人:

NOVARTIS AG

发明人:

Carnley NORMAN,Eric SUDA,Kayla DOWLESS,Ruiz ASTIGARRAGA,Patrick BASTEK,Vaishali YANNONE

申请号：

US15035302

公开号：

US20160287693A1

申请日:

2014.11.06

申请国别(地区):

US

年份:

2016

代理人:

摘要：

The present application discloses methods for removing residual impurities from protein preparations. Such methods include addition of an anionic detergent to a solution comprising proteins of interest and cellular contaminants under non-precipitating conditions and passing the solution through an ion exchange column.

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