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Hydrophobic Molecule-Induced Branched Polymer Aggregates And Their Use
专利权人:
Ray Yin;Yubei Zhang;Jing Pan;Dujie Qin
发明人:
Dujie Qin,Ray Yin,Jing Pan,Yubei Zhang
申请号:
US13978713
公开号:
US20140314664A1
申请日:
2012.01.06
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Symmetrically and asymmetrically branched homopolymers are modified at the surface level with functional groups that enable forming aggregates with water insoluble or poorly water soluble pharmaceutically active agents (PAA). The aggregates formed are specifically induced by interaction of PAA and homopolymer and are different from aggregates that are formed by the polymer alone in the absence of the PAA or by the PAA alone in the absence of the polymer. Such aggregates can be used to improve drug solubility, stability, delivery and efficacy.
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http://www.ckcest.cn/home/
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