KYOTO UNIVERSITY;JAPANESE FOUNDATION FOR CANCER RESEARCH
发明人:
Seishi Ogawa,Keisuke Kataoka,Kengo Takeuchi
申请号:
US15569898
公开号:
US10585100B2
申请日:
2016.04.28
申请国别(地区):
US
年份:
2020
代理人:
摘要:
An object of the present invention is to provide an effective method of predicting an effect of treatment by a PD-1/PD-L1 blockade, which is a method of predicting whether or not PD-1/PD-L1 blockade is effective for treatment of a subject suffering from a malignant tumor, which comprises detecting abnormality of genome relating to effectiveness of the PD-1/PD-L1 blockade in a tumor cell taken from the subject and evaluating the PD-1/PD-L1 blockade as useful for the treatment of the subject when there is the abnormality.