VACCIN INACTIVE CONTRE LA POLIOMYELITE

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专利权人:

THE SECRETARY OF STATE FOR HEALTH

发明人:

MACADAM, ANDREW

申请号：

CA2821859

公开号：

CA2821859C

申请日:

2011.12.29

申请国别(地区):

CA

年份:

2020

代理人:

摘要：

The invention provides an attenuated polio virus having a 5' non-coding regionconsisting of the 5' non-coding regionof Sabin 3, modified so that it does not have a base pair mismatch in stem (a)or (b) of domain V, wherein seven or eight of the basepairs in stems (a) and (b) are U-A or A-U base pairs； and a capsid proteinfrom the Sabin 1, Mahoney, MEF or Saukett strain.

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