治療試劑的CNS遞送

• 收藏
• 分享

专利权人:

SHIRE HUMAN GENETIC THERAPIES INC.

发明人:

Pericles CALIAS P,Jing PAN J,Jan POWELL J,Lawrence CHARNAS L,Thomas MCCAULEY T,Teresa Leah WRIGHT TL,Richard PFEIFER R,Zahra SHAHROKH Z,‧加萊斯,‧潘,‧鮑威爾,‧查納斯,‧麥考利,‧萊特,‧菲佛,‧夏若克

申请号：

HK16106769.8

公开号：

HK1218719A

申请日:

2016.06.13

申请国别(地区):

HK

年份:

2017

代理人:

摘要：

The present invention provides, among other things, compositions and methods for CNS delivery of lysosomal enzymes for effective treatment of lysosomal storage diseases. In some embodiments, the present invention includes a stable formulation for direct CNS intrathecal administration comprising an iduronate-2-sulfatase (I2S) protein, salt, and a polysorbate surfactant for the treatment of Hunters Syndrome.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/