Compounds (I) or pharmaceutically acceptable salts thereof are provided, which are TrkA kinase inhibitors and can be used to treat diseases that can be treated with TrkA kinase inhibitors, such as pain, cancer, inflammatory and inflammatory diseases, neurodegenerative diseases, certain infectious diseases, shegren's syndrome, endometriosis, diabetic peripheral neuropathy, prostatitis, pelvic pain syndrome Signs, diseases related to the imbalance of bone remodeling regulation, and diseases caused by abnormal signal transduction of connective tissue growth factor.提供了化合物(I)或其藥學上可接受的鹽，其爲TrkA激酶抑制劑並且可用於治療可用TrkA激酶抑制劑治療的疾病，諸如疼痛、癌症、炎症和炎性疾病、神經變性疾病、某些感染性疾病、舍格倫氏綜合征、子宮內膜異位、糖尿病性周圍神經病變、前列腺炎、盆腔疼痛綜合征、與骨重塑調節失衡相關的疾病以及由結締組織生長因子異常信號傳導引起的疾病。
