Disclosed herein are amide 7 carboxybenzo 1 2 3 thiadiazoles and derivatives thereof having a general Formula I as described herein. Combinations and compositions of these compounds are also disclosed. The compounds and compositions can be used as a plant stimulant. For example the compounds compositions can be used to regulate the plants growth regulate the plants metabolic processes regulate the plants physiological processes prevent against effects of biotic stress in the plant or prevent against effects of abiotic stress in the plant. In some embodiments the composition can provide multiple disease resistance to plants infected with a fungus virus or bacteria.