A respiratory assistance device used by a patient having a breathing problem. Specifically, the respiratory assistance device includes a blower for taking in gas and sending out the gas into the respiratory tract of the patient, an upstream-side humidifier for humidifying the gas to be introduced into the blower on the upstream side of the blower, and a downstream-side humidifier for humidifying the gas sent out from the blower on the downstream side of the blower.