KIM, BOK DEUK,김복득,YOO, DONG YOUL,유동열,KIM, SUNG YONG,김성용,PARK, YONG SUNG,박용성,PARK, IN SOON,박인순,LEE, YONG JAE,이용재,LEE, JIN KYOON,이진균
申请号:
KR1020110126067
公开号:
KR1020130059858A
申请日:
2011.11.29
申请国别(地区):
KR
年份:
2013
代理人:
摘要:
PURPOSE: A composition containing a Cinnamomum cassia Blume extract for promoting growth or preventing and treating osteoporosis is provided to enhance osteogenesis.CONSTITUTION: A pharmaceutical composition for promoting growth or preventing and treating osteoporosis contains a crude extract, a polar solvent soluble extract, or a non-polar solvent soluble extract of Cinnamomum cassia Blume as an active ingredient. The crude extract is prepared using a solvent selected from the group consisting of water, C1-C4 alcohols, or a mixture thereof. The polar solvent soluble extract is dissolved in a solvent selected among water, methanol, ethanol, butanol, or a mixture thereof. The non-polar solvent soluble extract is dissolved in a solvent selected from hexane, chloroform, and ethyl acetate. The composition contains 0.1-50 wt% of the extract.COPYRIGHT KIPO 2013본 발명은 육계(Cinnamomum cassia Blume)의 추출물을 유효성분으로 함유하는 발육 성장 촉진용 또는 골다공증의 예방 및 치료를 위한 조성물에 관한 것으로, 본 발명의 육계 추출물은 골세포의 분열능, 알칼리 포스파타아제 (Alkaline phosphatase) 활성, 콜라겐 합성 측정을 통해 골형성 증가 활성이 탁월함을 확인함으로써, 발육 성장 촉진용 또는 골다공증의 예방 및 치료용 약학조성물에 이용될 수 있다.