There is provided an exhaled breath moisture reduction system including a dryer mechanism and a connector adapted to connect the dryer mechanism proximate to a respiratory output device. There is also provided an exhaled breath sampling assembly including an airway adaptor and a moisture reduction sleeve comprising a material adapted to reduce moisture and a connector adapted to connect said sleeve substantially adjacent to a breath sampling inlet within the adaptor. Also provided, a method of sampling breath which includes attaching an exhaled breath moisture reduction sleeve substantially adjacent to a breath sampling inlet.