The present invention relates to an oil-in-water cosmetic composition, wherein high-content calamine is stabilized in an inner phase by using a mixture of a sorbitan-based surfactant and a sugar-based surfactant. The present invention also relates to a use of a mixture of a sorbitan-based surfactant and a sugar-based surfactant as an inner phase stabilizer in the preparation of an oil-in-water cosmetic composition containing high-content calamine in an inner phase. The present invention also relates to a method for stabilizing high-content calamine in an inner phase of an oil-in-water cosmetic composition. Furthermore, the present invention relates to a method for maximizing functional activity of calamine by applying, to the skin, the oil-in-water cosmetic composition containing a high-content calamine in an inner phase according to the present invention.本發明涉及在內相中穩定化高含量的爐甘石(Calamine)的水包油型化妝料組合物,其混合使用脫水山梨糖醇類表面活性劑及糖類表面活性劑。此外,本發明涉及在製備內相中含有高含量爐甘石的水包油型化妝料組合物中,脫水山梨糖醇類表面活性劑及糖類表面活性劑的混合物作為內相穩定劑的用途。此外,本發明涉及在水包油型化妝料組合物的內相中穩定化高含量的爐甘石的方法。進一步地,本發明涉及將本發明的在內相中穩定化高含量爐甘石的水包油型化妝料組合物應用於皮膚上,從而極大化爐甘石的功能性活性的方法。