An image processing device includes: an abnormality candidate region detection unit configured to detect, from an intraluminal image obtained by imaging a living body lumen, an abnormality candidate region in which a tissue characteristic of the living body or an in-vivo state satisfies a predetermined condition； a feature data calculation unit configured to calculate, from each of a plurality of regions inside the intraluminal image, a plurality of pieces of feature data including different kinds； an integrated feature data calculation unit configured to calculate integrated feature data by integrating the plurality of pieces of feature data based on information of the abnormality candidate region； and a detection unit configured to detect an abnormality from the intraluminal image by using the integrated feature data.
