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Compounds as histone deacetylase 6 inhibitors and pharmaceutical compositions comprising the same
专利权人:
CHONG KUN DANG PHARMACEUTICAL CORP.
发明人:
Hyeseung Song,Changgon Lee,Dalyong Kwak,Jaeyoung Lee,Suyeal Bae,Yuntae Kim,Daekwon Bae,Nina Ha,Miseon Bae,Jihyun Kim
申请号:
US15125256
公开号:
US10287255B2
申请日:
2015.03.12
申请国别(地区):
US
年份:
2019
代理人:
摘要:
A compound of formula (I), having histone deacetylase 6 (HDAC6) inhibitory activity,wherein X, Q, N, R1, R2, L, and n are as described, isomers thereof, or pharmaceutically acceptable salts thereof, the use thereof for the preparation of therapeutic medicaments, pharmaceutical compositions comprising the same, a method of treating disease using the composition, and methods for preparing the novel compounds. The novel compounds according to the present invention have histone deacetylase 6 (HDAC6) inhibitory activity, and are effective for the prevention or treatment of HDAC6-associated diseases, including cancer, inflammatory diseases, autoimmune diseases, neurological diseases and neurodegenerative disorders.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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