A kind of medical treatment/cosmetic is provided, is raw material for save one of property to be intrinsic polyanionic polysaccharide, there is high safety, because in not needing to produce using chemical cross-linking agent agent, and it can powder water-insoluble polyanionic polysaccharide is uniform in affected part. It is dispersed in matrix in medical treatment/cosmetic, including pedestal and powder, wherein substrate includes the first anion polysaccharide of water soluble salt and powder does not dissolve 1/10th seconds polyanionic polysaccharide of powder water soluble salt by water and treatment fluid contains acid anhydrides.