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THERAPEUTIC AGAINST ITCH
专利权人:
ЧУГАИ СЕЙЯКУ КАБУСИКИ КАЙСЯ (JP)
发明人:
ХИГУТИ Йосинобу (JP),КАСУТАНИ Кейко (JP),КИТАМУРА Хидетомо (JP),ХАСЕГАВА Масаказу (JP)
申请号:
RU2010127291/15
公开号:
RU2010127291A
申请日:
2008.12.05
申请国别(地区):
RU
年份:
2012
代理人:
摘要:
1. A prophylactic or therapeutic agent against pruritus that contains an NR10 antagonist as an active ingredient. ! 2. The prophylactic or therapeutic agent according to claim 1, wherein the NR10 antagonist is an antibody having neutralizing activity against NR10. ! 3. A prophylactic or therapeutic agent according to claim 2, wherein the antibody is a monoclonal antibody. ! 4. A prophylactic or therapeutic agent according to claim 3, wherein the antibody is a monoclonal antibody having neutralizing activity against human NR10. ! 5. A prophylactic or therapeutic agent according to any one of claims 2 to 4, wherein the antibody is a recombinant antibody. ! 6. A prophylactic or therapeutic agent according to any one of claims 2 to 4, wherein the antibody is a chimeric, humanized or human antibody. ! 7. The prophylactic or therapeutic agent according to claim 5, wherein the antibody is a chimeric, humanized or human antibody. ! 8. A method for the prevention or treatment of pruritus, which comprises the step of administering an NR10 antagonist. ! 9. The method of claim 8, wherein the NR10 antagonist is an antibody having neutralizing activity against NR10. ! 10. The method according to claim 9, where the antibody is a monoclonal antibody. ! 11. The method of claim 10, where the antibody is a monoclonal antibody having neutralizing activity against human NR10. ! 12. The method according to any one of claims 9 to 11, wherein the antibody is a recombinant antibody. ! 13. The method according to any one of claims 9 to 11, wherein the antibody is a chimeric antibody, a humanized antibody, or an antibody1. Профилактическое или терапевтическое средство против зуда, которое содержит в качестве активного ингредиента антагонист NR10. ! 2. Профилактическое или терапевтическое средство по п.1, где антагонист NR10 представляет собой антитело, обладающее нейтрализующей активностью против NR10. ! 3. Профилактическое или терапевтическое средство по п.2, где антитело представляет собо
来源网站:
中国工程科技知识中心
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