THE UNITED STATES GOVERNMENT AS REPRESENTED BY THE DEPARTMENT OF VETERANS;OREGON HEALTH &; SCIENCE UNIVERSITY
发明人:
Michael Riscoe,Aaron Nilsen,Galen Miley,Rolf Winter,Sovitj Pou,Jane Xu Kelly,Rozalia Dodean
申请号:
US15215103
公开号:
US10532983B2
申请日:
2016.07.20
申请国别(地区):
US
年份:
2020
代理人:
摘要:
Disclosed are derivative compounds of ELQ-300 that include an ester at position 4. These compounds have enhanced properties relative to ELQ-300. Also disclosed are pharmaceutical compositions comprising the compounds and methods of treating and preventing malaria infections involving administering the pharmaceutical compositions to the subject.